WebJul 3, 2024 · Nurr1 is a promising therapeutic target for neurodegenerative diseases, but mechanistic understand of its modulation is limited and Nurr1 modulators as tools are lacking. Here, non-steroidal anti ... WebMar 17, 2024 · Evidence and in silico analyses showed that TUSC7, miR-211, and Nurr1 may be involved in BC pathogenesis by ceRNET signaling axis. This study aimed to investigate the potential role of TUSC7/miR-211/Nurr1 ceRNET and rs2615499 variant as a novel cer-SNP in BC subjects. The expression assays were conducted by qPCR on …
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WebOct 19, 2024 · Since Nurr1 is presumed to reside in the nucleus, expression of cytoplasmic Nurr1 is found to correlate with decreased disease-specific survival and recurrence-free … WebJul 3, 2024 · Nurr1 is a promising therapeutic target for neurodegenerative diseases, but mechanistic understand of its modulation is limited and Nurr1 modulators as tools are … simplified home health
Dichotomous roles for the orphan nuclear receptor …
WebMar 16, 2024 · A putative model for Nurr1 binding to its response elements. (A) Nurr1258-RXRα98-IR5 model generated by Paradock; the DBDs are shown as electrostatic … WebDec 4, 2024 · Evidence is provided that Nurr1 is expressed in a neuron‐specific manner in AD‐related brain regions; specifically, it is selectively expressed in glutamatergic neurons in the subiculum and the cortex of both normal and AD brains. The orphan nuclear receptor Nurr1 (also known as NR4A2) is critical for the development and maintenance of … WebParadoxically, NURR1 silenced breast xenografts showed significantly. decreased growth in comparison to control, underscoring a biphasic role for NURR1 in breast cancer … simplified home office 2020